Course Solutions Uncategorized (Solved) : Bioinformatics Need Use Galaxy Set Experiment Given Files Unsure Begin Distributing Galaxy Q35533032 . . . .

(Solved) : Bioinformatics Need Use Galaxy Set Experiment Given Files Unsure Begin Distributing Galaxy Q35533032 . . . .

 

BIOINFORMATICS

I need to use Galaxy to set up an experiment on some givenfiles, but I am unsure how to begin.

  1. I am distributing a Galaxy History called:CG19FinalProjectDNADatasets containing:
    • Sacce1_AssemblyScaffolds.fasta <- Saccharomycescerevisiae Wild-Type Genome
    • Sacce1.ExternalModels.gff3 <- Saccharomycescerevisiae Wild-Type Genome Annotations
    • Scerevisiae_RAMutant_Genome.v02.fa <- Saccharomycescerevisiae Mutant Genome
    • Sacce1_chrVI-VII-VIII.fasta <- Saccharomycescerevisiae Chromosomes VI/VII/VIII Wild-Type Genome
    • All Datasets are from the Wild-TypeGenome
    • Dataset01:
      • SRR352492.sra_1.fastq
      • SRR352492.sra_2.fastq
    • Dataset02:
      • SRR352384.sra_1.fastq
      • SRR352384.sra_2.fastq
    • Dataset03:
      • SRR452441.csra_1.fastq
      • SRR452441.csra_2.fastq
    • The Datasets have already been Quality Controlled
    • Saccharomyces cerevisiae Wild-Type ChromosomesVI/VII/VIII is being provided for you to test/optimize your mappingconditions
  2. Your task is:
    • To use these NGS Datasets to identify any polymorphisms thatmight be present in theSaccharomyces cerevisiae MutantGenome
    • You are welcome to validate your findings using other methods(e.g., alignments, Blast, etc), but your
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